One-lung ventilation with capnothorax

Airway separation with unilateral lung closure (one-lung ventilation, OLV) is used to facilitate exposure during lung surgery and thoracoscopic surgery. In the latter case, insufflation of carbon dioxide may provide further optimization by compressing the lung. The respiration needs to be managed with one lung only and its related problem regarding CO2 elimination and oxygenation. There may also be a mismatch between perfusion and ventilation during OLV. There may be important hemodynamic side effects that require treatment. We have developed a model to explore the physiology during these conditions (1). The model has been used further to define the optimal conditions for this kind of ventilation and will be included in an upcoming doctoral thesis (Henrik Reinius)

  1. Reinius H, Borges JB, Fredén F, Jideus L, Camargo ED, Amato MB, Hedenstierna G, Larsson A, Lennmyr F. Real-time ventilation and perfusion distributions by electrical impedance tomography during one-lung ventilation with capnothorax. Acta Anaesthesiol Scand. 2015 Mar;59(3):354-68.

Group members

Henrik Reinius**, Joao Baptista Borges**, Lena Jideus, Filip Fredén**, Anders Larsson**, Göran Hedenstierna**, Fredrik Lennmyr

 **Collaboration with the Department of Anesthesiology and the Hedenstierna Laboratory.